==================== THE KASABACH–MERRITT PHENOMENON ==================== Large congenital hemangiomas may result in shunting of blood and high-output cardiac failure or entrapment of platelets and a thrombocytopenic coagulopathy and a potentially life-threatening hemorrhage (the Kasabach–Merritt syndrome or phenomenon) (Fig). The pathogenesis of congenital hemangiomas is poorly understood. There is an association with prematurity. Kasabach-Merritt phenomenon is a rare, life-threatening condition in which either of two specific vascular tumors (tufted angioma or kaposiform hemangioendothelioma) traps and destroys platelets, which are a component of blood that helps clotting. This condition is also associated with other abnormal clotting conditions in which there is excessive consumption of clotting factors. Kasabach-Merritt phenomenon does not occur in children with infantile hemangiomas. Tumors usually occur shortly after birth and are equally common in males and females. These ...
- Obtenir le lien
- X
- Autres applications
===============
The bronze baby syndrome: A complication of #phototherapy
===============
**The Bronze baby syndrome is the dark grey-brown pigmentation of skin, mucous membrane and urine following phototherapy. **Hepatic dysfunction has to be there for this condition to be present. We report a neonate with dark brown pigmentation of skin. Lesions were spread over the abdomen (Fig. 1), chest, back and both upper and lower limb after receiving phototherapy for neonatal jaundice.
**It is assumed that abnormal accumulation of photoisomer of bilirubin is the cause of this condition.
**The second cause postulated is abnormal hepatic function leading to copper-porpyhrin complex which is photodestroyed leading to brown pigmentation.
**The third explanation is accumulation of biliverdin leading to pigmentation.
**It should be differentiated from grey baby syndrome exclusively seen in neonates and very young infants receiving high doses of chloramphenicol. The infant is cyanosed, acidotic, has cold peripheries and has the signs of all of marked hyponia, poor feeding, vomiting, loose stools and a distended abdomen.
The bronze baby syndrome: A complication of #phototherapy
===============
**The Bronze baby syndrome is the dark grey-brown pigmentation of skin, mucous membrane and urine following phototherapy. **Hepatic dysfunction has to be there for this condition to be present. We report a neonate with dark brown pigmentation of skin. Lesions were spread over the abdomen (Fig. 1), chest, back and both upper and lower limb after receiving phototherapy for neonatal jaundice.
**It is assumed that abnormal accumulation of photoisomer of bilirubin is the cause of this condition.
**The second cause postulated is abnormal hepatic function leading to copper-porpyhrin complex which is photodestroyed leading to brown pigmentation.
**The third explanation is accumulation of biliverdin leading to pigmentation.
**It should be differentiated from grey baby syndrome exclusively seen in neonates and very young infants receiving high doses of chloramphenicol. The infant is cyanosed, acidotic, has cold peripheries and has the signs of all of marked hyponia, poor feeding, vomiting, loose stools and a distended abdomen.
FR; ** Le syndrome du bébé bronzé; est la pigmentation gris-brune foncée de la peau, des muqueuses et de l'urine après la photothérapie.
** Le dysfonctionnement hépatique doit être là pour que cette condition soit présente. Nous rapportons un nouveau-né avec une pigmentation brun foncé de la peau. Les lésions ont été réparties sur l'abdomen (figure 1), la poitrine, le dos et les deux membres supérieurs et inférieurs après avoir reçu la photothérapie pour la jaunisse néonatale.
** On suppose qu'une accumulation anormale de photo-isomère de la bilirubine est la cause de cette affection.
** La deuxième cause postulée est une fonction hépatique anormale conduisant au complexe cuivre-porpyhrine qui est photodétruit conduisant à la pigmentation brune.
** La troisième explication est l'accumulation de la biliverdine menant à la pigmentation.
** Il doit être différencié du syndrome du bébé gris exclusivement observé chez les nouveau-nés et chez les très jeunes nourrissons recevant de fortes doses de chloramphénicol. Le nourrisson est cyanosé, acidotique, a des périphéries froides et a les signes de toute hyponie marquée, mauvaise alimentation, vomissements, selles molles et un abdomen distendu.
** Le dysfonctionnement hépatique doit être là pour que cette condition soit présente. Nous rapportons un nouveau-né avec une pigmentation brun foncé de la peau. Les lésions ont été réparties sur l'abdomen (figure 1), la poitrine, le dos et les deux membres supérieurs et inférieurs après avoir reçu la photothérapie pour la jaunisse néonatale.
** On suppose qu'une accumulation anormale de photo-isomère de la bilirubine est la cause de cette affection.
** La deuxième cause postulée est une fonction hépatique anormale conduisant au complexe cuivre-porpyhrine qui est photodétruit conduisant à la pigmentation brune.
** La troisième explication est l'accumulation de la biliverdine menant à la pigmentation.
** Il doit être différencié du syndrome du bébé gris exclusivement observé chez les nouveau-nés et chez les très jeunes nourrissons recevant de fortes doses de chloramphénicol. Le nourrisson est cyanosé, acidotique, a des périphéries froides et a les signes de toute hyponie marquée, mauvaise alimentation, vomissements, selles molles et un abdomen distendu.
- Obtenir le lien
- X
- Autres applications
Posts les plus consultés de ce blog
==================== THE KASABACH–MERRITT PHENOMENON ==================== Large congenital hemangiomas may result in shunting of blood and high-output cardiac failure or entrapment of platelets and a thrombocytopenic coagulopathy and a potentially life-threatening hemorrhage (the Kasabach–Merritt syndrome or phenomenon) (Fig). The pathogenesis of congenital hemangiomas is poorly understood. There is an association with prematurity. Kasabach-Merritt phenomenon is a rare, life-threatening condition in which either of two specific vascular tumors (tufted angioma or kaposiform hemangioendothelioma) traps and destroys platelets, which are a component of blood that helps clotting. This condition is also associated with other abnormal clotting conditions in which there is excessive consumption of clotting factors. Kasabach-Merritt phenomenon does not occur in children with infantile hemangiomas. Tumors usually occur shortly after birth and are equally common in males and females. These ...
Commentaires
Enregistrer un commentaire